"XX flags which could affect the ability of a JVM to run with a profiling agent include: -XX:+AggressiveOpts (as this is experimental and changes, it could interfere); -XX:-EliminateZeroing (could cause unexpected behaviour as it violates Java spec); -XX:-ExtendedDTraceProbes (this is already a profiling agent, so could interfere with another); -Xrunhprof[:options] (this is already a profiling agent, so could interfere with another)."